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Merck

P0119

Anti-Purinergic Receptor P2Y14 (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-GPR105, Anti-P2YR14

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Product Name

Anti-Purinergic Receptor P2Y14 (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, rat

technique(s)

western blot: 1:200 using rat brain and lung lysates, and rat heart membranes

UniProt accession no.

Q15391

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... P2RY14(9934)
rat ... P2ry14(171108)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. P2Y14 is expressed in several tissues including brain, lung, and several cells of hematopoietic origin such as T lymphocytes and dendritic cells. This receptor is apparently involved in chemotaxis, maturation of immature dendritic cells, and neuroimmune regulation.

Immunogen

peptide CIELKSELGRKWHKASN corresponding to residues 172-188 of human P2Y14 extracellular loop.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

Preparation Note

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCR5931
SLCQ1321
SLCL3796
SLCG1285
SLCF6413

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Jennifer Patritti Cram et al.
eLife, 11 (2022-03-22)
Neurofibromatosis type 1 (NF1) is characterized by nerve tumors called neurofibromas, in which Schwann cells (SCs) show deregulated RAS signaling. NF1 is also implicated in regulation of cAMP. We identified the G-protein-coupled receptor (GPCR) P2ry14 in human neurofibromas, neurofibroma-derived SC

Related Content

Data Sheet - P0119

Instructions

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