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Merck

P1918

Pancuronium bromide

mAChR blocker, powder

Synonym(s):

1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide

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About This Item

Empirical Formula (Hill Notation):
C35H60Br2N2O4
CAS Number:
15500-66-0
Molecular Weight:
732.67
NACRES:
NA.77
PubChem Substance ID:
24278623
UNSPSC Code:
12352200
EC Number:
239-532-5
MDL number:
MFCD00079223
Beilstein/REAXYS Number:
4226892

Product Name

Pancuronium bromide,

InChI key

NPIJXCQZLFKBMV-YTGGZNJNSA-L

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

SMILES string

[Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6

form

powder

originator

Organon

Quality Level

100

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

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Application

Pancuronium Bromide has been used as an analgesic in various experiments.

Biochem/physiol Actions

Aminosteroidal neuromuscular blocking agent; skeletal muscle relaxant

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Organon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

Pancuronium bromide is a biquarternary amino steroid. It blocks muscarinic acetylcholine receptors (M2) in the heart. Pancuronium has vagolytic and sympathomimetic properties. It is associated with tachycardia and hypertension.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2373
BCCF0176
BCCK7854
BCCH7933
BCCB3719

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