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P9641

Nonaethylene glycol monododecyl ether

Name: Nonaethylene glycol monododecyl ether
Brand: SIGMA

nonionic surfactant

Synonym(s):

C₁₂E₉, Dodecyl nonaethylene glycol ether, Dodecylnonaglycol, Polidocanol, Polyoxyethylene (9) lauryl ether

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About This Item

Linear Formula:

HO(CH₂CH₂O)₉(CH₂)₁₁CH₃

CAS Number:

3055-99-0

Molecular Weight:

582.81

UNSPSC Code:

12161900

NACRES:

NA.25

PubChem Substance ID:

24899047

EC Number:

221-284-4

Beilstein/REAXYS Number:

1895308

MDL number:

MFCD00043375

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Properties

Quality Level

200

form

liquid

mol wt

micellar average mol wt 64,000

aggregation number

110

CMC

0.08

solubility

water: 100 mg/mL to turbid

density

1,004 g/cm³

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C30H62O10/c1-2-3-4-5-6-7-8-9-10-11-13-32-15-17-34-19-21-36-23-25-38-27-29-40-30-28-39-26-24-37-22-20-35-18-16-33-14-12-31/h31H,2-30H2,1H3

InChI key

ONJQDTZCDSESIW-UHFFFAOYSA-N

Description

General description

Nonaethylene glycol monododecyl ether [C12H25O(CH2CH2O)9H] (AEO9) is a non-ionic surfactant.

Application

Nonaethylene glycol monododecyl ether has been used in a study to assess a procedure for analyzing total lipid and triacylglycerol using bovine liver tissue. It has also been used in a study to investigate how particle size of aggregates can be measured by the concentration dependence of the amplitude of the autocorrelation function.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Unsaturated aminophospholipids are preferentially retained by the fast skeletal muscle CaATPase during detergent solubilization. Evidence for a specific association between aminophospholipids and the calcium pump protein.

R J Bick et al.

Archives of biochemistry and biophysics, 286(2), 346-352 (1991-05-01)

When fast twitch skeletal muscle vesicles (SR) and purified calcium pump protein are stripped with the nonionic detergent C12E8 (octaethylene glycol dodecyl ether), not all the membrane phospholipids are removed from the calcium pump protein. Maximal extraction produces a remnant

Identification of a phospholemman-like protein from shark rectal glands. Evidence for indirect regulation of Na,K-ATPase by protein kinase c via a novel member of the FXYDY family.

Y A Mahmmoud et al.

The Journal of biological chemistry, 275(46), 35969-35977 (2000-08-30)

The Na,K-ATPase provides the driving force for many ion transport processes through control of Na(+) and K(+) concentration gradients across the plasma membranes of animal cells. It is composed of two subunits, alpha and beta. In many tissues, predominantly in

Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979.

Amila Pramisandi et al.

The Journal of general and applied microbiology, 66(5), 273-278 (2020-07-17)

An Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979 was cultured to find novel scaffolds of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors. We obtained altenusin (1), which inhibits PfDHODH, with an IC50 value of 5.9 μM, along with other metabolites: mitorubrinol (2)

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