RAB0275

Mouse IL-1 β ELISA Kit

Name: Mouse IL-1 β ELISA Kit
Brand: SIGMA

for cell and tissue lysates

Synonym(s):

Cytokine detection kit

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About This Item

NACRES:

NA.32

UNSPSC Code:

41116158

Product Name

Mouse IL-1 β ELISA Kit, for cell and tissue lysates

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Il1b(16176)

Related Categories

Enzyme-Linked Immunosorbent Assay (ELISA) Kits

Immunoassay Platform Solutions

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Mouse IL-1 β ELISA Kit has been used to measure the concentration of interleukin 1 (IL)1-β in serum and bronchoalveolar lavage fluid (BALF) sample.

Biochem/physiol Actions

Interleukin 1 β (IL-1β) stimulates the production of endogenous 92 kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). It is a proinflammatory cytokine that induces various acute and chronic inflammation. Therefore, IL-1β can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1β brings neutrophil and macrophage to the site of infection. Over expression of IL-1β in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. Mutations in IL-1β gene leads to renal manifestations and renal sequelae in Henoch-Schonlein purpura (HSP).

General description

The Mouse IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1 β cell lysate and tissue lysate.

Immunogen

Recombinant Mouse IL-1 β

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

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Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis

Heun Y, et al.

EBioMedicine (2019)

Protective effects of fucoidan against hyperoxic lung injury via the ERK signaling pathway

Nie M, et al.

Molecular Medicine Reports, 17(1), 1813-1818 (2018)

Interleukin 1 beta (IL1?) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schonlein purpura.

Lopez-Mejias R

Clinical and Experimental Rheumatology, 34(3 Suppl 97), S84-S88 (2016)

Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders

Takahashi T, et al.

Oral Surgery, Oral Medicine, and Oral Pathology, 85(2), 135-141 (1998)

Strain- and host species-specific inflammasome activation, IL-1? release, and cell death in macrophages infected with uropathogenic Escherichia coli.

Schaale K

Mucosal Immunology, 9(1), 124-136 (2016)

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