S3889

D-Sorbitol

Name: <SC>D</SC>-Sorbitol
Brand: SIGMA

≥98% (GC), BioReagent, suitable for cell culture, suitable for plant cell culture

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₄O₆

CAS Number:

50-70-4

Molecular Weight:

182.17

UNSPSC Code:

12352201

NACRES:

NA.28

PubChem Substance ID:

24899573

EC Number:

200-061-5

Beilstein/REAXYS Number:

1721899

MDL number:

MFCD00004708

Product Name

D-Sorbitol, ≥98% (GC), BioReagent, suitable for cell culture, suitable for plant cell culture

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

product line

BioReagent

assay

≥98% (GC)

form

powder

technique(s)

cell culture | mammalian: suitable
cell culture | plant: suitable

color

white

useful pH range

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

Quality Level

200

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Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture & Analysis

Cell Culture Media & Buffers

Cell Culture Supplements & Reagents

Application

May be used for washing spheroplasts and in isoelectric focusing to minimize endoosmotic flow in agarose gels. May be used to induce osmotic stress.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Isoelectric focusing.

D E Garfin

Methods in enzymology, 182, 459-477 (1990-01-01)

Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults.

Arlene E Dent et al.

PloS one, 3(10), e3557-e3557 (2008-10-30)

Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

J M van Griensven et al.

Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)

To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

Electrocatalytic hydrogenation and deoxygenation of glucose on solid metal electrodes.

Youngkook Kwon et al.

ChemSusChem, 6(3), 455-462 (2013-01-25)

This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction

The phosphoinositide PI(3,5)P₂ mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells.

Anna Boccaccio et al.

Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)

Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large

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