S4751

Stearic acid

Name: Stearic acid
Brand: SIGMA

Grade I, ≥98.5% (capillary GC)

Synonym(s):

1-Heptadecanecarboxylic acid, C18:0, Cetylacetic acid, NSC 25956, NSC 261168, Octadecanoic acid, Stearophanic acid

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About This Item

Linear Formula:

CH₃(CH₂)₁₆COOH

CAS Number:

57-11-4

Molecular Weight:

284.48

UNSPSC Code:

12352106

NACRES:

NA.25

PubChem Substance ID:

24899616

EC Number:

200-313-4

Beilstein/REAXYS Number:

608585

MDL number:

MFCD00002752

Product Name

Stearic acid, Grade I, ≥98.5% (capillary GC)

InChI key

QIQXTHQIDYTFRH-UHFFFAOYSA-N

InChI

1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)

SMILES string

CCCCCCCCCCCCCCCCCC(O)=O

vapor pressure

1 mmHg ( 173.7 °C)

type

Grade I

assay

≥98.5% (capillary GC)

form

powder

bp

361 °C (lit.)

mp

67-72 °C (lit.)

solubility

chloroform: 100 mg/mL, clear, colorless

density

0.845 g/cm³

functional group

carboxylic acid

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

Quality Level

200

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Biochemicals

Coenzymes

Proteins & Enzymes

Application

Stearic acid has been used in fatty acid preparations.

Biochem/physiol Actions

β-Oxidation of stearic acid yields eight FADH2 (flavin adenine dinucleotide) and NADH2 (nicotinamide adenine dinucleotide) molecules and nine acetyl-CoA molecules.

General description

Stearic acid is a C₁₈ saturated fatty acid.

Storage Class

11 - Combustible Solids

wgk

nwg

flash_point_f

392.0 °F - Cleveland open cup

flash_point_c

200 °C - Cleveland open cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000523245

0000475512

0000513650

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Hypoxia potentiates palmitate-induced pro-inflammatory activation of primary human macrophages

Snodgrass Ryan G, et al.

The Journal of Biological Chemistry, 291(1), 413-424 (2016)

Construction and comparison of solid liquid phase diagrams of binary sat-sat and unsat-unsat fatty acid mixtures comprising two of palmitic/stearic/oleic/linoleic/linolenic acid

Eckert KA, et al.

Journal of Environmental Research And Development, 10(4), 1-1 (2016)

Solid liquid phase diagrams of binary fatty acid mixtures?Palmitic/stearic with oleic/linoleic/linolenic acid mixture

Eckert Karl-Andreas, et al.

Thermochimica Acta, 630, 50-63 (2016)

Sports Nutrition (1999)

Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition.

Hua Ning et al.

Nutrients, 8(4), 227-227 (2016-04-23)

The detrimental role of hepatic lipotoxicity has been well-implicated in the pathogenesis of NAFLD. Previously, we reported that inhibiting autophagy aggravated saturated fatty acid (SFA)-induced hepatotoxicity. Insulin, a physiological inhibitor of autophagy, is commonly increased within NAFLD mainly caused by

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