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Merck

S9512

Succinic acid

greener alternative

BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
110-15-6
Molecular Weight:
118.09
UNSPSC Code:
12352207
NACRES:
NA.71
PubChem Substance ID:
24899842
EC Number:
203-740-4
Beilstein/REAXYS Number:
1754069
MDL number:
MFCD00002789

Product Name

Succinic acid, BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

SMILES string

OC(=O)CCC(O)=O

product line

BioReagent

assay

≥99.0% ( with NaOH, titration)

form

powder

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

density

1.564 g/cm3 at 15 °C

greener alternative category

Aligned,

Quality Level

200

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Other Notes

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

Application

Use as a TCA (Krebs cycle) supplement in insect cell culture applications.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP0878
BCCN6472
BCCN1502
BCCM7019
BCCM6475

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Muhammad Fariz Ali et al.
Pathogens (Basel, Switzerland), 9(9) (2020-09-10)
To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vitro
Corey Osto et al.
Current protocols in cell biology, 89(1), e116-e116 (2020-12-16)
Measuring oxygen consumption allows for the role of mitochondrial function in biological phenomena and mitochondrial diseases to be determined. Although respirometry has become a common approach in disease research, current methods are limited by the necessity to process and measure
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
Hilal Taymaz-Nikerel et al.
Metabolic engineering, 16, 115-129 (2013-02-02)
The interactions between the intracellular metabolome, fluxome and growth rate of Escherichia coli after sudden glycolytic/gluconeogenic substrate shifts are studied based on pulses of different substrates to an aerobic glucose-limited steady-state (dilution rate=0.1h(-1)). After each added glycolytic (glucose) and gluconeogenic
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Product Information Sheet - S9512

Product Information Sheet

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