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Merck

SAB5600072

Anti-Phospho-STAT3 (Tyr705) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM261, purified immunoglobulin

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-Phospho-STAT3 (Tyr705) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM261, purified immunoglobulin

recombinant

expressed in HEK 293 cells

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM261, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunoblotting: 1:1000-1:2000
immunohistochemistry: 1:1000-1:10,000

isotype

IgG

NCBI accession no.

6774

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr705)

Quality Level

100

Gene Information

human ... STAT3(6774)

Biochem/physiol Actions

This antibody reacts to human Stat3 only when phosphorylated at Tyr705. There is no cross-reactivity to stat3 without phosphorylation at Tyr705. This antibody may also react to mouse or rat Phospho-Stat3 (Tyr705), as predicted by immunogen homology.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

Synthetic peptide corresponding to human Phospho-Stat3 (Tyr705)

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
R0301520
P1100799

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Chengliang Yuan et al.
Journal of biochemical and molecular toxicology, 36(1), e22943-e22943 (2021-11-02)
Eriocitrin, a lemons flavanone, exhibits several biological properties, antiproliferative, and proapoptotic effects. However, its molecular mechanical action is not entirely clarified. Oxidative stress causes abnormal stimulation of signal transducer and activator of transcription 3 (STAT3) and c-Jun NH2-terminal kinase (JNK), p38

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