SML0792
JW480
≥98% (HPLC)
Synonym(s):
2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate, JW 480
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About This Item
Empirical Formula (Hill Notation):
C22H23NO2
CAS Number:
Molecular Weight:
333.42
UNSPSC Code:
12352200
NACRES:
NA.77
SMILES string
N(CCc2cc3c(cc2)cccc3)C(=O)Oc1c(cccc1)C(C)C
InChI
1S/C22H23NO2/c1-16(2)20-9-5-6-10-21(20)25-22(24)23-14-13-17-11-12-18-7-3-4-8-19(18)15-17/h3-12,15-16H,13-14H2,1-2H3,(H,23,24)
InChI key
PCNJGBMWAZRVEA-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
JW480 is a highly potent and selective inhibitor of KIAA1363.
JW480 is a highly potent and selective inhibitor of KIAA1363. JW480 reduce MAGEs and impair the migration, invasion, survival, and in vivo tumor growth of human prostate cancer cell lines.
Storage Class
11 - Combustible Solids
wgk
WGK 3
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Yuchuan Li et al.
Cancer cell international, 23(1), 276-276 (2023-11-18)
Despite therapeutic advances, the prognosis of pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. Metabolic reprogramming is increasingly recognized as a key contributor to tumor progression and therapy resistance in PDAC. One of the main metabolic changes essential for tumor growth
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