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Merck

T0895

Thymine

BioReagent, suitable for cell culture

Synonym(s):

2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil

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About This Item

Empirical Formula (Hill Notation):
C5H6N2O2
CAS Number:
65-71-4
Molecular Weight:
126.11
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24899920
EC Number:
200-616-1
Beilstein/REAXYS Number:
117880
MDL number:
MFCD00006026
Assay:
≥99% (HPLC)
Biological source:
synthetic
Form:
powder
Solubility:
1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

Key Documents

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InChI key

RWQNBRDOKXIBIV-UHFFFAOYSA-N

InChI

1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

SMILES string

CC1=CNC(=O)NC1=O

biological source

synthetic

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

~320 °C (dec.) (lit.)

solubility

1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

Quality Level

200

Gene Information

mouse ... Tymp(72962)

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH5708
BCCF8975
BCCF4949
BCBZ9526
BCBZ5310

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S I Ahmad et al.
Annual review of microbiology, 52, 591-625 (1999-01-19)
For many years it has been known that thymine auxotrophic microorganisms undergo cell death in response to thymine starvation [thymineless death (TLD)]. This effect is unusual in that deprivation of many other nutritional requirements has a biostatic, but not lethal
Javier A Tello et al.
American journal of physiology. Endocrinology and metabolism, 305(1), E67-E77 (2013-05-02)
The human GnRH receptor (GNRHR1) has a specific set of properties with physiological and pharmacological influences not appropriately modeled in laboratory animals or cell-based systems. To address this deficiency, we have generated human GNRHR1 knock-in mice and described their reproductive
Stefano Stella et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 9), 1707-1716 (2013-09-04)
Transcription activator-like effectors contain a DNA-binding domain organized in tandem repeats. The repeats include two adjacent residues known as the repeat variable di-residue, which recognize a single base pair, establishing a direct code between the dipeptides and the target DNA.
Subhendu Sekhar Bag et al.
The Journal of organic chemistry, 78(2), 278-291 (2012-11-23)
We report the design and synthesis of triazolyl donor/acceptor unnatural nucleosides via click chemistry and studies on the duplex stabilization of DNA containing two such new nucleosides. The observed duplex stabilization among the self-pair/heteropair has been found to be comparable
U Hardeland et al.
Progress in nucleic acid research and molecular biology, 68, 235-253 (2001-09-14)
More than 50% of colon cancer-associated mutations in the p53 tumor suppressor gene are C-->T transitions. The majority of them locate in CpG dinucleotides and are thought to have arisen through spontaneous hydrolytic deamination of 5-methylcytosine. This deamination process gives
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