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MABC303 Anti-PELP1 Antibody, clone 2F11.1

Anti-PELP1 Antibody, clone 2F11.1 is an antibody against PELP1 for use in Western Blotting, Immunocytochemistry.

Anti-PELP1 Antibody, clone 2F11.1 : MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PELP1, HMX3, MNAR UniProt Number: Q8IZL8
MABC303
100 μg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC303
DescriptionAnti-PELP1 Antibody, clone 2F11.1
Alternate Names
  • Proline-, glutamic acid- and leucine-rich protein 1
  • PELP1
  • Modulator of non-genomic activity of estrogen receptor
  • Transcription factor HMX3
Background InformationProline-, glutamic acid- and leucine-rich protein 1 (UniProt Q8IZL8; also known as Modulator of non-genomic activity of estrogen receptor, p160, Proline and glutamic acid rich nuclear protein,Transcription factor HMX3) is encoded by the PELP1 (Also known as HMX3, MNAR, P160) gene in human (Gene ID 27043). PELP1 functions as scaffolding protein and mediates protein–protein interactions in cellular processes involving both genomic and extranuclear signaling pathways. Multiple structural domains allow PELP1 to interact with various steroid receptors (SRs) to modulate their activity as either corepressor or coactivator. Dysregulation of PELP1 expression has been observed in breast, ovarian, endometrial, brain, and prostate cancers.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-PELP1 Antibody, clone 2F11.1 is an antibody against PELP1 for use in Western Blotting, Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: 5 µg/mL from a representative lot detected PELP1 in HeLa and A431 cells.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human PELP1.
Clone2F11.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PELP1
  • HMX3
  • MNAR
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~160 kDa observed. PELP1/MNAR has a predicted molecular weight of 120 kDa and an isoelectric point of 4.30, but because of the overall negative charge and excessive amount of prolines, the protein migrates on SDS-PAGE as a 160-kDa protein (Rajhans, R., and Vadlamudi, R.K. (2006). Clin. Exp. Metastasis. 23(1):1-7).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected PELP1 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
MABC303 04055977169836