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204870 Complement C3d, Human

204870
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Products

Numero di catalogoConfezionamento Qtà/conf
204870-100UG Fiala di plastica 100 μg
Description
OverviewNative, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.
Catalogue Number204870
Brand Family Calbiochem®
References
ReferencesLuxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.
Product Information
CAS number18282-10-5, 1317-80-2, 12001-26-2, 52004-97-4, 1344-43-0, 21645-51-2, 57-11-4
FormLiquid
FormulationIn PBS, pH 7.2.
PreservativeNone
Quality LevelMQ100
Applications
Biological Information
Purity≥85% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsIgG, IgM, IgA, C5, Factor H, Factor I: ≤trace amounts
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Complement C3d, Human MSDS

Titolo

Scheda di sicurezza (MSDS) 

Complement C3d, Human Certificati d'Analisi

TitoloNumero di lotto
204870

Riferimenti bibliografici

Panoramica delle referenze
Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-May-2008 RFH
DescriptionNative, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30,000. The binding of C3d to CR2 (CD21) receptors present on B-lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.
FormLiquid
FormulationIn PBS, pH 7.2.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number18282-10-5, 1317-80-2, 12001-26-2, 52004-97-4, 1344-43-0, 21645-51-2, 57-11-4
Purity≥85% by SDS-PAGE
ContaminantsIgG, IgM, IgA, C5, Factor H, Factor I: ≤trace amounts
PreservativeNone
Storage ≤ -70°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesLuxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.