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Merck

GS500

Giemsa Stain, Modified

Synonym(s):

Giemsa Solution

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About This Item

NACRES:
NA.47
PubChem Substance ID:
24895392
UNSPSC Code:
41116121
MDL number:
MFCD00081642

Key Documents

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InChI

1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H

SMILES string

[Cl-].CN(C)c1ccc2N=C3C=CC(=[NH2+])C=C3Sc2c1

InChI key

NALREUIWICQLPS-UHFFFAOYSA-N

form

solution

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

concentration

0.4 % (w/v) in buffered methanol solution, pH 6.8, with stabilizers

technique(s)

microbe id | staining: suitable

pH

6.75-6.95

application(s)

hematology
histology

storage temp.

room temp

Quality Level

500

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Application

When blood films are stained using Giemsa Stain, the nucleus and cytoplasm of white blood cells take on characteristic blue or pink coloration. The use of purified eosin and thiazine dyes minimizes lot-to-lot variation.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Alcohols + Hazardous rank II

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

GS500-VAR: + GS500-BULK: + GS500-500ML:4548173198842

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Certificates of Analysis (COA)

Lot/Batch Number
0000506128
0000506128
0000383024
0000383024
0000380814

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Cell Migration (2005)
Histophatologic Techniques (2006)
Jing Zhang et al.
Cell death & disease, 11(7), 602-602 (2020-08-01)
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor and has the highest mortality rate among cancers and high resistance to radiation and cytotoxic chemotherapy. Although some targeted therapies can partially inhibit oncogenic mutation-driven proliferation of GBM cells, therapies
The Giemsa stain: its history and applications
Barcia, et al,
International Journal of Surgical Pathology, 15(3) (2007)
Liat Peretz et al.
Scientific reports, 8(1), 93-93 (2018-01-10)
Inhibition of genes is a powerful approach to study their function. While RNA interference is a widely used method to achieve this goal, mounting evidence indicates that such an approach is prone to off-target effects. An alternative approach to gene
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An overview of the science and practice of bacteriology in clinical diagnostics. Learn more about the application of standard and special stains for microscopic analysis.

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Learn about the clinical study of blood, blood-forming organs, and blood diseases including the treatment, prevention, and stains and dyes used in hematology testing.

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