14-721-M
EGFR (T790M, L858R) Protein, active, 10 µg
Active, N-terminal GST-tagged, recombinant human EGFR, amino acids 696-end containing the mutations T790M & L858R, for use in Enzyme Assays.
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この商品について
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf21 cells
Mol wt:
Mw 85.8 kDa
biological source
human
Quality Segment
recombinant
expressed in baculovirus infected Sf21 cells
product line
Upstate®
specific activity
(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
mol wt
Mw 85.8 kDa
purified by
(Glutathione-agarose)
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable
accession no.
(FUNCTION: SwissProt: P00533 # Isoform 2/truncated isoform may act as an antagonist. ), NM_005228.3
NCBI accession no.
UniProt accession no.
relevant disease(s)
arthritis; obesity; osteoporosis; metabolic disorders
General description
EGFR
N-terminal GST-tagged, recombinant human EGFR, amino acids 696end containing the mutations T790M and L858R
Application
Research Category
Metabolism
Inflammation & Immunology
Metabolism
Inflammation & Immunology
Research Sub Category
Obesity
Metabolic Disorders
Osteoporosis
Arthritis
Obesity
Metabolic Disorders
Osteoporosis
Arthritis
Biochem/physiol Actions
Protein Target: EGFR
Target Sub-Family: TK
Packaging
Also available in 10 μg size and in bulk
Physical form
Glutathione-agarose
Preparation Note
6 months at -70°C from date of shipment
Analysis Note
routinely evaluated by phosphorylation of 250μM substrate peptide (GGMEDIYFEFMGGKKK)
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_c
Not applicable
試験成績書（COA）
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