05-1416
Anti-CD45 Antibody, clone IBL-5/25
clone IBL-5/25, from rat
å¥å:
CD45 associated protein, CD45-associated protein, Lymphocyte phosphatase-associated phosphoprotein, PTPRC-associated protein, protein tyrosine phosphatase, receptor type, C-associated protein, protein tyrosine phosphatase, receptor type, c
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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
IBL-5/25, monoclonal
Application:
FACS, IHC
Citations:
21
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ãæäŒãããŸãQuality Segment
biological source
rat
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
IBL-5/25, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable, immunohistochemistry: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Ptprc(19264)
General description
CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.
Approx. 147 kDa
Immunogen
Mouse lymph node cells.
Application
Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes
Biochem/physiol Actions
Reactivity with other species has not been determined.
This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
FUSION PARTNER: SP2/0 myeloma cell line
FUSION PARTNER: SP2/0 myeloma cell line
Physical form
Format: Purified
Purified rat monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.
Preparation Note
Store at 2-8°C for 12 months from date of receipt.
Analysis Note
Control
Mouse colon tissue
Mouse colon tissue
Evaluated by Immunohistochemistry in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL1326
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