05-645
Anti-phospho-HSP27 (Ser78) Antibody, clone JBW502
clone JBW502, Upstate®, from mouse
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
JBW502, monoclonal
Species reactivity:
human
Application:
WB
Citations:
6
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
JBW502, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pSer78)
Quality Level
Gene Information
human ... HSPB2(3316)
General description
27kDa
Immunogen
peptide corresponding to amino acids 73-83 of human HSP27 with a C-terminus cysteine added for conjugation (YSRAL[pS]RQLSS-C)
Application
Anti-phospho-HSP27 (Ser78) Antibody, clone JBW502 is an antibody against phospho-HSP27 (Ser78) for use in WB.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Chaperones
Chaperones
Biochem/physiol Actions
phosphorylated HSP27 (Ser78)
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on phosphorylated HSP27 in 20mg of a cell lysate prepared from MCF-7 cells that were heat shocked for 30 minutes at 42°C, cultured for an additional 16 hours at 37°C, and then stimulated with 200mM arsenite for 30 minutes
Other Notes
Replaces: 04-447
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
wgk
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
05-645:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer.
Zhang, D; Wong, LL; Koay, ES
Molecular Cancer null
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation.
Park, KJ; Gaynor, RB; Kwak, YT
The Journal of Biological Chemistry null
Yusuke Tamura et al.
Molecular oncology, 15(5), 1289-1307 (2020-12-21)
Development of innovative therapeutic modalities would address an unmet clinical need in the treatment of triple negative breast cancer (TNBC). Activation of retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) such as melanoma differentiation-associated gene 5 (MDA5) and RIG-I in cancer cells
Eugene Chang et al.
Blood, 117(8), 2527-2537 (2010-12-07)
Actin filament remodeling regulates several endothelial cell (EC) processes such as contraction, migration, adhesion, and shape determination. Mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2)-mediated phosphorylation of heat-shock protein 27 kDa (HSP27) promotes actin filament remodeling, but little is known
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 05-645 | 04053252730306 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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