07-328
Anti-acetyl-Histone H4 (Lys8) Antibody
serum, Upstate®
別名:
H4K8Ac, Histone H4 (acetyl K8)
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human, Saccharomyces cerevisiae
Application:
ChIP, DB, IP, WB
Citations:
92
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, Saccharomyces cerevisiae
manufacturer/tradename
Upstate®
technique(s)
ChIP: suitable (ChIP-seq), dot blot: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys8)
Quality Level
Gene Information
human ... H4C1(8359)
General description
Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.
The N-terminal tail of histone H4 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
The N-terminal tail of histone H4 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
10 kDa
Immunogen
Peptide corresponding to amino acids 3-13 of yeast Histone H4 (RGKGGAcKGLGKG-C) in which lysine 8 is acetylated.
Application
Use Anti-acetyl-Histone H4 (Lys8) Antibody (Rabbit Polyclonal Antibody) validated in ChIP, IP, WB, DB, ChIP-seq to detect acetyl-Histone H4 (Lys8) also known as H4K8Ac, Histone H4 (acetyl K8).
Analysis Note
Control
Sodium butyrate treated HeLa cells
Sodium butyrate treated HeLa cells
routinely evaluated by immunoblot on acid extracts from sodium butyrate treated HeLa cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
07-328:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy.
Urbinati G, Marsaud V, Plassat V, Fattal E, Lesieur S, Renoir JM
International Journal of Pharmaceutics null
Cc Chemokine Ligand 2 and Lif Cooperatively Promote Pluripotency in Mouse Induced Pluripotent Cells.
Hasegawa Y, Takahashi N, Forrest AR, Shin JW, Kinoshita Y, Suzuki H, Hayashizaki Y
Stem Cells null
Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl.
Vaughan, CA; Singh, S; Windle, B; Yeudall, WA; Frum, R; Grossman, SR; Deb, SP; Deb, S
Genes & Cancer null
Shivakumar Subbanna et al.
The international journal of neuropsychopharmacology, 18(5) (2015-01-23)
Ethanol exposure to rodents during postnatal day 7 (P7), which is comparable to the third trimester of human pregnancy, induces long-term potentiation and memory deficits. However, the molecular mechanisms underlying these deficits are still poorly understood. In the present study
Xiangsong Chen et al.
eLife, 5 (2016-11-23)
Leaf senescence is an essential part of the plant lifecycle during which nutrients are re-allocated to other tissues. The regulation of leaf senescence is a complex process. However, the underlying mechanism is poorly understood. Here, we uncovered a novel and
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 07-328 | 04053252324789 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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