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1.02839

L-システイン 塩酸塩 一水和物

for biochemistry

別名:

Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate

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この商品について

化学式:
HSCH2CH(NH2)COOH · HCl · H2O
CAS番号:
7048-04-6
分子量:
175.63
UNSPSC Code:
12352209
NACRES:
NA.21
EC Index Number:
200-157-7
MDL number:
MFCD00065606
Beilstein/REAXYS Number:
5158059
Assay:
98.5-101.0% dry basis (alkalimetric)
Form:
crystalline powder
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vapor pressure

<0.1 hPa ( 20 °C)

Quality Segment

100

assay

98.5-101.0% dry basis (alkalimetric)

form

crystalline powder

pH

0.8-1.2 (20 °C, 100 g/L in H2O)

mp

168-170 °C

solubility

650 g/L

density

1.54 g/cm3

bulk density

780 kg/m3

anion traces

sulfate (SO42-): ≤300 ppm

cation traces

Fe: ≤20 ppm, heavy metals (as Pb): ≤10 ppm

storage temp.

2-30°C

SMILES string

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

InChI key

QIJRTFXNRTXDIP-JIZZDEOASA-N

Application


  • Smartphone-based Ellman′s colourimetric methods for the analysis of d-penicillamine formulation and thiolated polymer: Demonstrates the application of L-Cysteine hydrochloride monohydrate in developing colorimetric assays for pharmaceutical analysis, enhancing the accessibility and cost-effectiveness of drug quality control (Phadungcharoen et al., 2019).

  • The effects of the thiolation with thioglycolic acid and l-cysteine on the mucoadhesion properties of the starch-graft-poly(acrylic acid): Focuses on the modification of polymers with L-Cysteine hydrochloride monohydrate to improve their mucoadhesive properties, which is critical for developing more effective drug delivery systems (Gök et al., 2017).

  • On-line pre-reduction of pentavalent arsenicals by thioglycolic acid for speciation analysis by selective hydride generation-cryotrapping-atomic absorption spectrometry: Utilizes L-Cysteine hydrochloride monohydrate in analytical chemistry techniques to improve the detection and measurement of toxic elements in environmental samples, crucial for monitoring and ensuring public health (Musil et al., 2008).

Biochem/physiol Actions

N-メチル-D-アスパラギン酸(NMDA)型グルタミン酸作動性受容体のアゴニストです。

Analysis Note

Assay (alkalimetric, calculated on dried substance): 98.5 - 101.0 %
Identity (IR-spectrum): passes test
Identity (Chloride): passes test
Appearance: white or almost white, crystalline powder or colorless crystals
Appearance of solution (25 g/l, water): clear and not more intense in color than reference solution BY6
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance): +5.5 to +7.0
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance): +5.7 to +6.8
Sulfate (SO₄): ≤ 300 ppm
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 20 ppm
Related Compounds, total (TLC): ≤ 0.5 %
Ninhydrin-positive substances (LC)(impurity A (570 nm)): ≤ 0.5 %
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 1.0 %
Residual solvents (ICH Q3C): excluded by manufacturing process
Sulfated ash (600 °C): ≤ 0.1 %
Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h): 8.0 - 12.0 %
Bacterial endotoxins: ≤ 6.0 I.U./g

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保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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