1.09333
LiChrosorb® RP-18 (5 µm)
HPLC sorbent
別名:
TM=["LiChrosorb"] C18 sorbent for HPLC
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この商品について
製品名
LiChrosorb® RP-18 (5 µm),
material
stainless steel column
agency
suitable for USP L1
product line
LiChrosorb®
feature
endcapped: no
analyte functional class(es)
antibiotics, explosives, fat soluble vitamins, lipids, nutraceuticals and antioxidants, oils, pigments, sweeteners, water soluble vitamins
analyte chemical class(es)
PAHs, PCBs (aroclor identification), PFAS, aflatoxins, alcohols / fermentation, alcohols and aldehyde, aliphatic amines, alkaloids, amino acids, aromatic amines, cannabinoids as tms derivatives, carotenoids, catecholamines, coloring compounds, essential oils, esters, fatty acids, flavonoids, glycans, ketones, metabolized steroids, nitrosamines, nucleic acids, nucleosides, oligonucleotides, organic phosphates, peptides, pesticides, phenols, phospholipids, phthalate esters, preservatives, proteins, steroids (cholesteryl esters), sulfonamides
parameter
60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low)
matrix
fully porous particle
matrix active group
C18 (RP18), C18 bonding phase
particle size
10 μm
pore size
100 Å pore size
operating pH range
2-7.5
bulk density
200‑400 kg/m3
separation technique
reversed phase
storage temp.
no temp limit
General description
Application
- Determination of berberine in human serum by reversed-phase high performance liquid chromatography.: This study outlines a method for detecting berberine in human serum using reversed-phase HPLC, utilizing the LiChrosorb RP-18 column for its reliability in separating chemical compounds in biological samples (Sun Y et al., 1997).
- Kinetics of hydrolysis of 4-methoxy-2-[2-hydroxy-3(4-phenyl-1-piperazinyl)]propyl-2,3-dihydro-6-methyl-1,3-dioxo-1H-pyrrolo[3,4-c]pyridine in aqueous solutions.: This research employs RP-18 to study the stability and hydrolysis kinetics of a complex organic compound, highlighting its application in pharmaceutical analysis (Muszalska I et al., 2004).
- A validated spectrophotometric and liquid chromatography method for determination and purity evaluation of 4-methoxy-2-[2-hydroxy-3(4-phenyl-1-piperazinyl)]propyl-2,3-dihydro-6-methyl-1,3-dioxo-1H-pyrrolo[3,4-c]pyridine.: This paper details the use of RP-18 in validating a method for assessing the purity of pharmaceutical compounds, demonstrating its essential role in quality control (Muszalska I et al., 2003).
- High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study utilizes RP-18 to monitor fluconazole in clinical samples, providing insights into the pharmacokinetics and therapeutic monitoring of antifungal treatment in HIV patients (Beijnen JH et al., 1995).
- Ion-pair solid-phase extraction of cimetidine from plasma and subsequent analysis by high-performance liquid chromatography.: Describes a method using RP-18 for the extraction and analysis of cimetidine, a drug used to treat heartburn and peptic ulcers, from plasma samples, illustrating its versatility in drug analysis (Russel FG et al., 1994).
Analysis Note
stability testing (performance): passes test
separation factor (Acetophenone/Phenol, selectivity test): 1.8 - 2.2
separation factor (Acetophenone/Cinnamic acid, selectivity test): 1.1 - 1.4
separation factor (1-Naphtol/Phenol, selectivity test): 3.9 - 4.7
capacity factor (Toluene): 16.0 - 21.0
Particle Size (d10): 3.8 - 4.3 µm
Particle Size (d50): 6.7 - 7.7 µm
Particle Size (d90): 12.0 - 14.0 µm
Legal Information
保管分類
11 - Combustible Solids
一体何が起きているの？
nwg
引火点 (F)
Not applicable
引火点（°C）
Not applicable