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Merck

1.09334

LiChrosorb® RP-18 (10 µm) HPLC Columns

HPLC sorbent

別名:

TM=["LiChrosorb"] C18 sorbent for HPLC

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この商品について

UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
10 μm
Matrix active group:
C18 (RP18), C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
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製品名

LiChrosorb® RP-18 (10 µm),

material

stainless steel column

agency

suitable for USP L1

product line

LiChrosorb®

feature

endcapped: no

analyte functional class(es)

antibiotics, explosives, fat soluble vitamins, lipids, nutraceuticals and antioxidants, oils, pigments, sweeteners, water soluble vitamins

analyte chemical class(es)

PAHs, PCBs (aroclor identification), PFAS, aflatoxins, alcohols / fermentation, alcohols and aldehyde, aliphatic amines, alkaloids, amino acids, aromatic amines, cannabinoids as tms derivatives, carotenoids, catecholamines, coloring compounds, essential oils, esters, fatty acids, flavonoids, glycans, ketones, metabolized steroids, nitrosamines, nucleic acids, nucleosides, oligonucleotides, organic phosphates, peptides, pesticides, phenols, phospholipids, phthalate esters, preservatives, proteins, steroids (cholesteryl esters), sulfonamides

parameter

60 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (Low)

matrix

fully porous particle

matrix active group

C18 (RP18), C18 bonding phase

particle size

10 μm

pore size

100 Å pore size

operating pH range

2-7.5

bulk density

200‑400 kg/m3

separation technique

reversed phase

storage temp.

no temp limit

Application


  • High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study highlights a method using RP-18 for the determination of fluconazole, demonstrating the column′s effectiveness in bioanalytical contexts (Beijnen JH et al., 1995).

  • Determination of serum aluminium using an ion-pair reversed-phase high-performance liquid chromatographic-fluorimetric system with lumogallion.: This research utilizes RP-18 to analyze serum aluminum, showcasing its utility in trace metal analysis in clinical samples (Ong CN et al., 1995).

  • A radiochemical high-performance liquid chromatographic method for the analysis of 2-fluoro-2-deoxy-D-glucose-derived metabolites in human chondrocytes.: The method developed employs RP-18, underscoring its role in the radiochemical analysis of complex biological matrices (Greiling H et al., 1993).

  • Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.: This study demonstrates the application of RP-18 in the pharmacokinetic analysis of cephalosporins, further proving the column′s broad applicability in pharmaceutical analyses (Juge F et al., 1983).

  • Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection.: This research uses RP-18 to simultaneously quantify multiple neurotransmitters, highlighting its sensitivity and specificity for neurochemical analysis (Huot S et al., 1982).


Analysis Note

Theoretical Plates (N/m) (Toluene): ≥ 25000
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 - 10.0 µm
particle size (Malvern) (d50): 12.0 - 14.0 µm
particle size (Malvern) (d90): 17.5 - 20.5 µm

Legal Information

LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany


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保管分類

11 - Combustible Solids

一体何が起きているの?

nwg

引火点 (F)

Not applicable

引火点(°C)

Not applicable



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