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1.19637

LiChrospher® 100 RP-18 endcapped (5 µm)

HPLC sorbent

別名:

TM=["LiChrospher"] C18 sorbent for HPLC

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この商品について

UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
5 μm
Matrix active group:
C18 (RP18), C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
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製品名

LiChrospher® 100 RP-18 endcapped (5 µm),

material

stainless steel column

agency

suitable for USP L1

product line

LiChrospher®

feature

endcapped

analyte functional class(es)

antibiotics, explosives, fat soluble vitamins, lipids, nutraceuticals and antioxidants, oils, pigments, sweeteners, water soluble vitamins

analyte chemical class(es)

PAHs, PCBs (aroclor identification), PFAS, aflatoxins, alcohols / fermentation, alcohols and aldehyde, aliphatic amines, alkaloids, amino acids, aromatic amines, cannabinoids as tms derivatives, carotenoids, catecholamines, coloring compounds, essential oils, esters, fatty acids, flavonoids, glycans, ketones, metabolized steroids, nitrosamines, nucleic acids, nucleosides, oligonucleotides, organic phosphates, peptides, pesticides, phenols, phospholipids, phthalate esters, preservatives, proteins, steroids (cholesteryl esters), sulfonamides

packaging

1 ea of

extent of labeling

21.6% Carbon loading

parameter

60 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)

surface area

350 m2/g

matrix

fully porous particle

matrix active group

C18 (RP18), C18 bonding phase

particle size

5 μm

pore size

100 Å pore size

operating pH range

2-7.5

bulk density

200‑400 kg/m3

separation technique

reversed phase

storage temp.

no temp limit

General description

LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with revered phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Application


  • Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD: The robustness of the LiChrospher® 60 RP-select B column is highlighted in forensic science, where it is used to accurately identify and quantify cannabinoids, demonstrating its critical role in legal and forensic analyses (Ambach et al., 2014).

  • RP-HPLC separation and characterization of unknown impurities of a novel HIV-protease inhibitor Darunavir by ESI-MS and 2D NMR spectroscopy: The LiChrospher® 60 RP-select B column′s exceptional selectivity and performance are utilized to identify novel impurities in Darunavir, highlighting its application in developing more effective HIV treatments (Nageswara Rao et al., 2013).

  • Quantification of pralidoxime (2-PAM) in urine by ion pair chromatography-diode array detection: Demonstrating versatility, this column was used to detect therapeutic agents in clinical settings, supporting treatment regimes for poisonings where rapid and accurate drug monitoring is essential (John et al., 2012).


Analysis Note

Application test: passes test
Pressure: ≤ 50 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm

Legal Information

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類

11 - Combustible Solids

一体何が起きているの？

nwg

引火点 (F)

Not applicable

引火点（°C）

Not applicable

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