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Merck

178479

Anti-Apolipoprotein E Goat pAb

liquid, Calbiochem®

別名:

Anti-ApoE antibody

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この商品について

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
—
Citations:
57

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biological source

goat

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human, rat, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:8000)
Immunoprecipitation
Free Floating Sections )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

General description

Anti-Apolipoprotein E, goat polyclonal, recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins. It is validated for ELISA, immunoprecipitation, and free-floating sections.
Goat polyclonal antibody supplied as serum that has been defibrinated, delipidized and dialyzed against a Tris-HCl buffer. Recognizes the apolipoprotein E protein.
Recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins.
  • Antibody Target Gene Symbol: APOE
  • Target Synonym: AD2, AI255918, APOE2, APOE4, APOEA, APOLIPOPROTEIN E, LDLCQ5, LPG, MGC1571
  • Entrez Gene Name: apolipoprotein E
  • Hu Entrez ID: 348 (Related Antibodies: NE1004)
  • Mu Entrez ID: 11816
  • Rat Entrez ID: 25728

    • Immunogen

    Human
    purified recombinant human apolipoprotein E

    Application

    ELISA (1:8000)

    Immunoprecipitation (see comments)

    Free Floating Sections (see application references)

    Packaging

    Please refer to vial label for lot-specific concentration.

    Physical form

    In 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.

    Preparation Note

    Following initial thaw, aliquot and freeze (-20°C).

    Other Notes

    Monospecific as determined by immunoelectrophoresis (IEP) against twice concentrated pooled human serum. This antibody has also been reported to work with immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Disclaimer

    Toxicity: Standard Handling (A)

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    保管分類

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    適用法令

    試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

    178479-UL: + 178479-5ML: + 178479-500UL: + 178479-0ML:

    jan

    試験成績書（COA）

    製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

    以前この製品を購入いただいたことがある場合

    文書ライブラリで、最近購入した製品の文書を検索できます。

    文書ライブラリにアクセスする

    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Daniel Da Costa et al.
    Journal of virology, 86(21), 11919-11925 (2012-08-17)
    Hepatitis C virus (HCV) is a human hepatotropic virus, but the relevant host factors restricting HCV infection to hepatocytes are only partially understood. We demonstrate that exogenous expression of defined host factors reconstituted the entire HCV life cycle in human
    Jin-Dong Ding et al.
    Proceedings of the National Academy of Sciences of the United States of America, 108(28), E279-E287 (2011-06-22)
    Age-related macular degeneration (AMD) is a leading cause of visual dysfunction worldwide. Amyloid β (Aβ) peptides, Aβ1-40 (Aβ40) and Aβ1-42 (Aβ42), have been implicated previously in the AMD disease process. Consistent with a pathogenic role for Aβ, we show here
    Nicholas F Fitz et al.
    Journal of Alzheimer's disease : JAD, 41(2), 535-549 (2014-03-20)
    Passive amyloid-β (Aβ) vaccination has shown significant effects on amyloid pathology in pre-depositing amyloid-β protein precursor (AβPP) mice but the results in older mice are inconsistent. A therapeutic effect of LXR and RXR agonists consisting of improved memory deficits and
    Suzanne E Wahrle et al.
    The Journal of clinical investigation, 118(2), 671-682 (2008-01-19)
    APOE genotype is a major genetic risk factor for late-onset Alzheimer disease (AD). ABCA1, a member of the ATP-binding cassette family of active transporters, lipidates apoE in the CNS. Abca1(-/-) mice have decreased lipid associated with apoE and increased amyloid
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    グローバルトレードアイテム番号

    カタログ番号GTIN
    178479-500ULCN04055977205183

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