Quality Segment
assay
≥95% (SDS-PAGE)
form
liquid
specific activity
≥150,000 C9H50 units/mg
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
impurities
IgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8, trace
shipped in
wet ice
storage temp.
−70°C
General description
Native, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Stanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
12 - Non Combustible Liquids
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適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
204910-UG: + 204910-250UG: + 204910-0MG: + 204910-5MG:
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