345744
Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain
Inhibits Con A-stimulated mitogenesis in murine T cells.
別名:
Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain, Neu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH4
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この商品について
実験式（ヒル表記法）:
C95H162N5O47 · 3NH4
分子量:
2180.42
NACRES:
NA.77
UNSPSC Code:
12352211
Assay:
≥98% (TLC)
Form:
lyophilized
Storage condition:
OK to freeze
Quality Segment
assay
≥98% (TLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
ethanol: soluble, methanol: soluble
shipped in
ambient
storage temp.
−20°C
General description
Inhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.
M.W. 2180.5 (based on stearoyl - 18:0).
Trisialoganglioside prepared from bovine gray matter. Readily converted to GD1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.
Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inhibits Con A-stimulated mitogenesis in murine T cells
Inhibits Con A-stimulated mitogenesis in murine T cells
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.
Other Notes
Hakomori, S. 1985. Cancer Res.45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta441, 488.
Warren, L. 1959. J. Biol. Chem.234, 1971.
Momoi, T., et al. 1976. Biochim. Biophys. Acta441, 488.
Warren, L. 1959. J. Biol. Chem.234, 1971.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
345744-1MG: + 345744-UG:
jan