420355
Isoprenaline hydrochloride
≥99% (TLC), solid, β-adrenoceptor agonist, Calbiochem
別名:
Isoproterenol, Hydrochloride
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
実験式（ヒル表記法）:
C11H17NO3 · xHCl
CAS番号:
分子量:
211.26 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥99% (TLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
製品名
Isoproterenol, Hydrochloride, Phenethylamine derivative.
description
Merck USA index - 14, 5217
Quality Segment
assay
≥99% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white to off-white, white
solubility
ethanol: soluble, water: soluble
shipped in
ambient
storage temp.
10-30°C
SMILES string
[Cl-].N(C(C)C)CC(O)c1cc(c(cc1)O)O.[H+]
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key
IROWCYIEJAOFOW-UHFFFAOYSA-N
General description
Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.
Biochem/physiol Actions
Cell permeable: no
Primary Target
β-adrenergic agonist
β-adrenergic agonist
Product does not compete with ATP.
Reversible: no
Preparation Note
Unstable in solution; reconstitute just prior to use.
Other Notes
Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.
Yashiro, K., et al. 1994. J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.
Yashiro, K., et al. 1994. J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
保管分類
11 - Combustible Solids
一体何が起きているの？
WGK 2
引火点 (F)
No data available
引火点（°C）
No data available