454575
N-Methyl-D-aspartic Acid hydrate
>95% (TLC), solid, excitatory amino acid neurotransmitter, Calbiochem®
別名:
N-Methyl-D-aspartic Acid, Hydrate, NMDA
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
実験式（ヒル表記法）:
C5H9NO4 · xH2O
CAS番号:
分子量:
147.13 (anhydrous basis)
UNSPSC Code:
12352209
NACRES:
NA.77
MDL number:
Assay:
>95% (TLC)
Form:
solid
Storage condition:
OK to freeze
製品名
N-Methyl-D-aspartic Acid, Hydrate, Excitatory amino acid neurotransmitter.
Quality Segment
description
Merck USA index - 14, 6662
assay
>95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
10-30°C
SMILES string
N([C@H](CC(=O)O)C(=O)[O-])C
InChI
1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/p-1/t3-/m1/s1
InChI key
HOKKHZGPKSLGJE-GSVOUGTGSA-M
General description
An excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
Excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Glutamate receptor that regulates Ca2+ channels
Glutamate receptor that regulates Ca2+ channels
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
Other Notes
Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
一体何が起きているの？
WGK 3
引火点 (F)
Not applicable
引火点（°C）
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
454575-MG: + 454575-100MG:
jan