497985
Ornithine Decarboxylase Inhibitor, POB - Calbiochem
別名:
N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB, Ornithine Decarboxylase Inhibitor, POB - Calbiochem
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この商品について
化学式:
C19H31N3O6
NACRES:
NA.28
UNSPSC Code:
12352200
Form:
(White to off-white solid)
Storage condition:
OK to freeze
form
(White to off-white solid)
storage condition
OK to freeze
solubility
soluble (H2O (1 mg/ml))
storage temp.
2-8°C
General description
A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells.