552233
QX-314
≥99% (HPLC), lyophilized solid, voltage-sensitive Na+ conductance blocker, Calbiochem®
別名:
QX-314
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この商品について
実験式（ヒル表記法）:
C16H27BrN2O
CAS番号:
分子量:
343.30
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥99%
Form:
lyophilized solid
Storage condition:
OK to freeze, protect from light
製品名
QX-314, A quaternary lidocaine derivative, permanently charged, and lipophobic.
Quality Segment
assay
≥99%
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
solubility
water: 3 mg/mL
shipped in
ambient
storage temp.
10-30°C
SMILES string
[N+](CC)(CC)(CC)CC(=O)Nc1c(cccc1C)C
InChI
1S/C16H26N2O/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5/h9-11H,6-8,12H2,1-5H3/p+1
InChI key
PYEBKOFMWAMBFV-UHFFFAOYSA-O
General description
A quaternary lidocaine derivative, permanently charged, and lipophobic. A powerful blocker of voltage-sensitive Na+ conductance when applied intracellularly. Suppresses the generation of Na+-dependent spikes from inside the cell membrane, without affecting Ca2+ currents or glutamate-activated currents.
Biochem/physiol Actions
Cell permeable: no
Primary Target
A powerful blocker of voltage-sensitive Na+ conductance
A powerful blocker of voltage-sensitive Na+ conductance
Product does not compete with ATP.
Reversible: no
fully active in neurophysiological testing
Other Notes
Mooney, R. 1992. J. Neurosci.12, 2464.
Regehr, W.G. and Tank, D.W. 1992. J. Neurosci.12, 4202.
Regehr, W.G. and Tank, D.W. 1992. J. Neurosci.12, 4202.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。