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Taurocholic Acid, Sodium Salt

Name: Taurocholic Acid, Sodium Salt
Brand: MM

Detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number: 4.

別名:

Taurocholic Acid, Sodium Salt, Sodium Taurocholate

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この商品について

実験式（ヒル表記法）:

C₂₆H₄₄NO₇S · Na

CAS番号:

145-42-6

分子量:

537.68

UNSPSC Code:

12352106

NACRES:

NA.21

MDL number:

MFCD00013050

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特性

Quality Segment

100

description

Merck USA index - 14, 9075

assay

≥90% (TLC)

form

solid

mol wt

micellar wt 2100

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

aggregation number

color

white

pKa

1.9

CMC

3 - 11 mM

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].[S](=O)(=O)([O-])CCNC(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)C[C@@H]2O)CC1)C)C

InChI

1S/C26H45NO7S.Na/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;/m1./s1

InChI key

JAJWGJBVLPIOOH-IZYKLYLVSA-M

詳細

General description

Detergent useful for the solubilization of lipids and membrane-bound proteins (aggregation number: 4; CMC: 3-11 mM; micellar weight: 2100; pK_a: 1.9).

Application

Discovery of Taurocholic Acid Sodium Hydrate as a Novel Repurposing Drug for Intervertebral Disc Degeneration by Targeting MAPK3.: This research highlights the therapeutic potential of taurocholic acid, sodium salt in treating intervertebral disc degeneration. By targeting the MAPK3 pathway, it offers a new approach to managing spinal disorders, reflecting its significance in developing innovative treatments (Li P et al., 2024).

Effects of extraction methods and particle size distribution on the structural, physicochemical, and functional properties of dietary fiber from deoiled cumin.: This research uses taurocholic acid, sodium salt to investigate the optimization of dietary fiber extraction, contributing to advancements in food chemistry and health-related product development (Ma MM et al., 2016).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c