GF319
BMP-2, Human Recombinant
Animal Free
Synonym(s):
BMP2, BMP 2A, BMP 2, BMP2A, bone morphogenetic protein 2
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405
General description
BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues including lung, liver, spleen, prostate, ovary, and small intestine. Recombinant human BMP-2 is a 26.0 kDa homodimeric disulfide-linked protein consisting of two identical 115 amino acid chains.
Analysis Note
Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
Certificates of Analysis (COA)
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