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Merck

HKI4MAG-99K

MILLIPLEX® Human Kidney Injury Panel

Configurable Human Kidney Toxicity 7-plex Panel 4

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この商品について

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


製品名

MILLIPLEX® Human Kidney Injury Panel,

Quality Segment

description

Configurable Human Kidney Toxicity 7-plex Panel 4

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 63-118%, intra-assay cv: <10, sensitivity: 0.01-0.71 ng/mL
(MinDC+2SD), standard curve range: 0.01-5 ng/mL
(IP-10), standard curve range: 0.012-12.5 ng/mL
(EGF), standard curve range: 0.02-20 ng/mL
(PTH), standard curve range: 0.15-150 ng/mL
(FABP1), standard curve range: 0.17-1,200 ng/mL
(Osteopontin (OPN)), standard curve range: 0.20-200 ng/mL
(KIM-1), standard curve range: 0.68-700 ng/mL
(Renin)

technique(s)

multiplexing: suitable

input

serum
plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Albumin, Beta-2 Microglobulin, Clusterin, Cystatin C, and Lipocalin-2/NGAL are important biomarkers for evaluating kidney function, tubular integrity, and early signs of renal injury. These analytes help detect glomerular filtration changes, proteinuria, and inflammation, making them valuable for monitoring acute and chronic kidney conditions. Their combined assessment supports sensitive and specific evaluation of renal health.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in human serum or plasma samples.

Analytes included: α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN)

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:


  • Measures 7 key biomarkers of kidney injury in human urine samples

  • Includes α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, and Osteopontin (OPN)

  • Magnetic bead-based format for enhanced precision and simplified washing

  • Utilizes Luminex® xMAP® technology for multiplexing and high-throughput analysis

  • Validated for human urine with recommended sample dilution of 1:100

  • Assay sensitivity ranges from 0.015 to 5.359 ng/mL depending on the analyte

  • Standard curve ranges from 0.01 to 5,000 ng/mL across analytes

  • Intra-assay CV < 10%, inter-assay CV < 20%
Benefits:

  • Enables early and specific detection of kidney injury before traditional markers like BUN and serum creatinine



  • Provides insight into organ-specific damage and mechanisms of nephrotoxicity

  • Conserves sample volume by analyzing multiple biomarkers in a single run

  • Supports drug safety and toxicity research with high analytical performance

  • Reduces assay variability and improves reproducibility across studies

  • Compatible with both manual and automated workflows for flexible lab integration

Legal Information

Luminex is a registered trademark of Luminex Corporation
xMAP is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

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pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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