HMMP1MAG-55K
MILLIPLEX® Human MMP Panel
Configurable Human MMP 3-Plex Panel
別名:
Human matrix metalloproteinase multiplex kit, Luminex® Human MMP immunoassay, Millipore human MMP panel
ログインで組織・契約価格をご覧ください。
この商品について
UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
製品名
MILLIPLEX® Human MMP Panel, Configurable Human MMP 3-Plex Panel
Quality Segment
product line
Milliplex®
species reactivity
human
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
standard curve range: 146-150,000 pg/mL
(MMP-3), standard curve range: 58-60,000 pg/mL
(MMP-13), standard curve range: 98-100,000 pg/mL
(MMP-12)
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
plasma
serum
urine
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
MMPs (matrix metalloproteinases), a family of zinc proteases responsible for the breakdown of extracellular matrix (ECM), play a key role in normal physiological processes, such as embryonic development and tissue morphogenesis, tissue and bone remodeling, wound healing, and angiogenesis. These processes rely on MMPs′ role in the cleavage of cell surface receptors, the release of apoptotic ligands, cell proliferation and differentiation, and chemokine activity modulation. Similar in structure, MMPs are synthesized and secreted as inactive pro-enzymes that require proteolytic cleavage for activation. This process can be mediated by serine proteases or other MMPs. An increase in MMP expression occurs in response to a wide range of stimuli, including adhesion molecules, growth factors, cytokines, and hormones. Regulation of MMP activity is controlled primarily by TIMPs (tissue inhibitors of metalloproteinases). Therefore, disruption of the MMP/TIMP balance can result in arthritis, cardiovascular disease and tumor growth and metastasis.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 3 analytes in human serum, plasma, urine, and cell culture supernatants.
Analytes included: MMP-3, MMP-12, MMP-13
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: MMP-3, MMP-12, MMP-13
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Targeted 3-Plex Design: Focused Luminex® xMAP® magnetic bead platform specifically quantitates MMP-3, MMP-12, and MMP-13 simultaneously, providing concentrated analysis of key tissue remodeling enzymes in a single well.
- Broad Sample Compatibility: Analytically verified across serum, plasma, urine, tissue/cell lysates, and culture supernatants with neat sample processing - no dilution required for most applications.
- Streamlined Workflow: Optimized 3-analyte configuration delivers fast, one-day results while maximizing sample conservation and minimizing hands-on time for research studies.
- Precision Research Focus: Concentrate on three critical MMPs involved in tissue degradation and remodeling processes, enabling targeted investigation of specific pathological pathways in inflammation research.
- Mechanistic Research Applications: Target MMPs specifically associated with collagen degradation (MMP-3, MMP-13) and elastin breakdown (MMP-12) to investigate tissue destruction mechanisms in arthritis, cardiovascular, and pulmonary research.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Still not finding the right product?
Explore all of our products under MILLIPLEX® Human MMP Panel
注意喚起語
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - STOT RE 2
標的臓器
Respiratory Tract
保管分類
10 - Combustible liquids
一体何が起きているの？
WGK 3
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Please refer to KIT Component information
pdsc
Please refer to KIT Component information
prtr
Please refer to KIT Component information
fsl
Please refer to KIT Component information
ishl_indicated
Please refer to KIT Component information
ishl_notified
Please refer to KIT Component information
cart
キットコンポーネントの情報を参照してください
jan