MILLIPLEX^® Mouse Myokine Panel

Skeletal muscle functions as an endocrine organ by secreting myokines—proteins that regulate muscle growth, metabolism, and inter-organ communication. This panel—BDNF, Erythropoietin (EPO), FGF-21, Follistatin-like Protein 1 (FSTL1), IL-6, IL-15, Irisin, LIF, Myostatin/GDF8, Oncostatin M (OSM), Osteocrin (OSTN)/Musclin, and Osteonectin/SPARC—captures key indicators of muscle activity, inflammation, and metabolic regulation. The MILLIPLEX^® Mouse Myokine Panel enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting research in exercise physiology, metabolic disease, and muscle biology.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 12 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes Included: Brain Derived Neurotrophic Factor (BDNF), Erythropoietin (EPO), Fibroblast Growth Factor 21 (FGF-21), Follistatin-like Protein 1 (FSTL1), IL-6, IL-15, Irisin, Leukemia Inhibitory Factor (LIF), Myostatin (MSTN/GDF8), Oncostatin M (OSM), Osteocrin (OSTN/Musclin), Osteonectin (SPARC)
Note: Substantial amounts of BDNF are stored in circulating platelets and subsequently released upon platelet activation. Therefore, platelet-poor plasma is critical to ensure accurate measurement of circulating levels of BDNF. Erythropoeitin (EPO) is for tissue culture samples only and cannot be combined with other analytes in this panel when measuring serum or plasma.
Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features:

• Targets myokines involved in muscle growth, metabolism, inflammation, and inter-organ communication
• Includes 12 analytes relevant to skeletal muscle physiology and systemic metabolic regulation
• Multiplex format enables simultaneous detection from minimal sample volume
• Compatible with mouse serum, plasma, and cell/tissue culture supernatants
• Designed for research in exercise physiology, metabolic disorders, and muscle regeneration

Benefits:

• Provides a comprehensive profile of myokines for studying muscle-derived signaling
• Supports investigation of exercise-induced metabolic and immune responses
• Facilitates evaluation of therapeutic interventions in obesity, diabetes, and sarcopenia
• Enables high-throughput analysis with reduced sample and reagent use
• Delivers reproducible, sensitive results for preclinical and translational research

Luminex is a registered trademark of Luminex Corporation

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.