AB5832
Anti-BACE Antibody
Chemicon®, from rabbit
別名:
ASP2, BACE1, Beta Secretase, beta-Site APP Cleaving Enzyme
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
12
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BACE1(23621)
Immunogen
Synthetic peptide corresponding to amino acids 458 to 501 of human BACE (Vassar et al. 1999).
Application
Anti-BACE Antibody is an antibody against BACE for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western blotting: 0.5-1.0 μg/mL on human brain tissue. The antibody recognizes a protein of molecular weight of 70 kDa in normal human brain lysate.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reacts with human BACE by Western blot.
Physical form
Format: Purified
Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
AB5832:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Daisuke Tanokashira et al.
eNeuro, 2(2) (2015-10-16)
The β-secretase called BACE1 is a membrane-associated protease that initiates the generation of amyloid β-protein (Aβ), a key event in Alzheimer's disease (AD). However, the mechanism of intraneuronal regulation of BACE1 is poorly understood. Here, we present evidence that low-density
Naomi Mamada et al.
Molecular brain, 8(1), 73-73 (2015-11-11)
β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is a membrane-bound aspartyl protease that initiates amyloid β-protein (Aβ) generation. Aberrant elevation of BACE1 levels in brains of Alzheimer's disease (AD) patients may involve Aβ. In the present study, we used
D Porquet et al.
Age (Dordrecht, Netherlands), 37(1), 9747-9747 (2015-02-11)
The amyloid precursor protein/presenilin 1 (APP/PS1) mouse model of Alzheimer's disease (AD) has provided robust neuropathological hallmarks of familial AD-like pattern at early ages, whereas senescence-accelerated mouse prone 8 (SAMP8) has a remarkable early senescence phenotype with pathological similarities to
Yoshitaka Uno et al.
Human gene therapy, 22(6), 711-719 (2010-12-21)
We originally reported the use of vitamin E (α-tocopherol) as an in vivo vector of short-interfering RNA (siRNA) to the liver. Here, we apply our strategy to the brain. By combining high-density lipoprotein (HDL) as a second carrier with α-tocopherol-conjugated
Gurdeep Marwarha et al.
Journal of neurochemistry, 144(6), 761-779 (2018-01-10)
The etiology of Alzheimer's disease (AD) is egregiously comprehended, but epidemiological studies have posited that diets rich in the saturated fatty acid palmitic acid (palmitate) are a significant risk factor. The production and accumulation of amyloid beta peptide (Aβ) is
関連コンテンツ
Alzheimer’s Disease: Amyloid Cascade and Beyond Product Focus
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| AB5832 | 04053252739392 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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