ABD136
Anti-LGI1 Antibody
from rabbit, purified by affinity chromatography
別名:
Leucine-rich glioma inactivated protein 1, Epitempin-1
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
species reactivity (predicted by homology)
human (immunogen homology)
technique(s)
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... LGI1(9211)
General description
Leucine-rich glioma inactivated gene 1 (LGI1), also known as Epitempin-1 (EPT), is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) regulating voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. LGI1 may play a role in the control of neuroblastoma cell survival and may play a role in other cancers. It is expressed in neural tissue, especially brain. Mutations in LGI1 have been associated with nearly half of autodominant lateral temporal epilepsy (ADTLE).
~56 kDa observed. Uniprot describes 3 isoforms at ~33 kDa, ~58 kDa, and ~64 kDa Uncharacterized bands may appear in some lysates.
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human LGI1.
Application
Detect LGI1 using this rabbit polyclonal antibody, Anti-LGI1 Antibody validated for use in western blotting.
Biochem/physiol Actions
This antibody recognizes the N-terminus of LGI1.
Analysis Note
Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected LGI1 in 15 µg of mouse brain tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected LGI1 in 15 µg of mouse brain tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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保管分類
12 - Non Combustible Liquids
wgk
WGK 2
試験成績書（COA）
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