Anti-DBN1 Antibody

Drebrin (Developmentally-regulated brain protein) is also known by the gene name DBN1. Drebrins are found in the cytoplasm of brain neurons as well as tissues including heart, placenta skeletal muscle kidney and pancreas. Debrin binds F-actin and is involved in the mechanisms of development, cell migration, neuronal processes and dendrite plasticity.

~110 kDa observed. The calculated molecular weight is 71 kDa, however DBN1 has been shown as a ~110 kDa band in western blotting (Maezawa, I., et al. (2006).

KLH-conjugated linear peptide corresponding to human DBN1.

Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected DBN1 in human cerebellum and rat midbrain tissues.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This DBN1 antibody is validated for use in WB & IHC for the detection of the DBN1 protein.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Mouse brain tissue lysate

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected DBN1 in 10 µg of mouse brain tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: AB15288

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