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Merck

ABN478

Anti-LFG Antibody

from rabbit, purified by affinity chromatography

別名:

Protein lifeguard 2, Fas apoptotic inhibitory molecule 2, Neural membrane protein 35, Transmembrane BAX inhibitor motif-containing protein 2, LFG

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (immunogen homology)

technique(s)

immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FAIM2(23017)

General description

Protein lifeguard 2 (LFG) is an antiapoptotic protein belonging to the BI1 family. LFG inhibits the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-death signal. LFG is expressed at high levels in the brain especially in the hippocampus. It is also highly expressed in breast cancer tissues and correlates with the grade of tumor (grade II/grade III) in primary breast tumors.
~35 kDa observed.

Immunogen

KLH-conjugated linear peptide corresponding to human LFG.

Application

Detect LFG using this rabbit polyclonal antibody, Anti-LFG Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected LFG in mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
EL4 cell lysate
Evaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected LFG in 15 µg of EL4 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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WGK

WGK 2

保管分類

12 - Non Combustible Liquids



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