Anti-NETO1 Antibody

Neuropilin and tolloid-like protein 1, also known as Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, and encoded by the gene name NETO1 or BTCL1, is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal Nmethyl- D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.

~55 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human NETO1.

Anti-NETO1 Antibody detects level of NETO1 & has been published & validated for use in NETO1.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human lung tissure lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected NETO1 in human lung tissure lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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