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Merck

ABS568

Anti-RBP4 Antibody

from rabbit, purified by affinity chromatography

別名:

Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RBP4(5950)

General description

The role of the protein retinol binding protein 4 (RBP4) has always been understood to be involvement in the transport of vitamin A. However, research has demonstrated that blood levels of RBP4 is closely linked with the development of insulin resistance, which predisposes individuals to type 2 diabetes and is a major risk factor for cardiovascular disease. In addition higher levels of RBP4 were closely associated with other components of metabolic syndrome, including increased body mass index, waist-to-hip ratio, serum triglyceride levels and systolic blood pressure, as well as decreased HDL levels. Further investigations indicate that RBP4 may be a useful biomarker in identifying a predisposition to type 2 diabetes and measuring therapeutic improvement.
~23 kDa observed

Immunogen

Recombinant protein corresponding to human RBP4.

Application

Anti-RBP4 Antibody is a highly specific rabbit polyclonal antibody, that targets Retinol binding protein 4 & has been tested in western blotting.
Research Category
Signaling
Research Sub Category
Metabolic Hormones & Receptors
Western Blotting Analysis: 2.0 µg/mL from a representative lot detected RBP4 in 10 µg of human spleen, thymus, ovary and testis tissue lysates.

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected RBP4 in 10 µg of human liver tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABN1095

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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ABS568:

jan



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