CBL468
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6
clone HC1/6, Chemicon®, from mouse
別名:
CD31
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HC1/6, monoclonal
Application:
flow cytometry
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
immunoprecipitation (IP)
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
immunoprecipitation (IP)
Species reactivity:
human
Citations:
15
Technique(s):
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
製品名
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6, clone HC1/6, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
HC1/6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PECAM1(5175)
Analysis Note
Control
Activated microglial cells
Activated microglial cells
Application
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Immunogen
Epitope: domains 3-6 of human PECAM-1
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Gina Lisignoli et al.
Journal of cellular physiology, 220(2), 401-409 (2009-04-15)
Bone marrow stromal cells (MSCs) and osteoblasts are the two main non-haematopoietic cellular components of human bone tissue. To identify novel osteoblast-related molecules, we performed a gene expression profiling analysis comparing MSCs and osteoblasts isolated from the same donors. Genes
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
T M Herndon et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5654-5664 (2001-04-21)
The transcription factor NF-kappaB is a critical regulator of T cell function that becomes strongly activated in response to coengagement of TCR and CD28. Although events immediately proximal to NF-kappaB activation are well understood, uncertainty remains over which upstream signaling
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| CBL468 | 04053252331015 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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