GF342
LIF,
Human Recombinant Animal Free
別名:
Leukemia Inhibitory Factor, Emfilermin, MLPLI, HILDA, D-FACTOR
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この商品について
UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
General description
LIF is a pleiotrophic factor produced by multiple cell types including T cells, myelomoncytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor.
Recombinant human LIF is a 19.6 kDa protein containing 180 amino acids residues including three disulfide bonds.
Recombinant human LIF is a 19.6 kDa protein containing 180 amino acids residues including three disulfide bonds.
Analysis Note
Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤0.1 ng/ml, corresponding to a specific activity of ≥1 x 10^7 units/mg.
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
GF342:
jan