MAB1681
Anti-Vimentin Antibody
CHEMICON®, mouse monoclonal, LN-6
別名:
Vimentin
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この商品について
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
LN-6, monoclonal
Species reactivity:
human, mouse
Application:
immunohistochemistry
Technique(s):
immunohistochemistry: suitable (paraffin)
Citations:
12
Uniprot accession no.:
製品名
Anti-Vimentin Antibody, clone LN-6, culture supernatant, clone LN-6, Chemicon®
biological source
mouse
antibody form
culture supernatant
antibody product type
primary antibodies
clone
LN-6, monoclonal
mol wt
calculated mol wt 53.65 kDa
observed mol wt ~N/A kDa
species reactivity
human, mouse
packaging
antibody small pack of 1
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
isotype
IgM
epitope sequence
Unknown
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
-10 to -25°C
target post-translational modification
unmodified
Gene Information
human ... VIM(7431)
Application
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Analysis Note
Control
Hyperplastic lymph nodes.
Hyperplastic lymph nodes.
Biochem/physiol Actions
Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
57-60 kDa
Immunogen
Nuclei from adult human thymic biopsy specimens.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Liquid tissue culture supernatant containing 0.02% sodium azide.
Preparation Note
Please refer to guidance on suggested starting dilutions and/or titers per application and sample type.
Store at -10°C to -25°C. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
MAB1681:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Paola Valdivieso et al.
PloS one, 12(4), e0174864-e0174864 (2017-04-07)
Mechanical stress, including blood pressure related factors, up-regulate expression of the pro-angiogenic extracellular matrix protein tenascin-C in skeletal muscle. We hypothesized that increased capillarization of skeletal muscle with the repeated augmentation in perfusion during endurance training is associated with blood
Liqing Wang et al.
The Journal of comparative neurology, 524(11), 2322-2334 (2016-01-01)
Expression of Nogo protein was investigated in the optic pathway of embryonic mice by using isoform-specific antibodies Bianca and 11C7, which recognize Nogo-A/B and Nogo-A, respectively. Our previous reports from using antibody N18 have shown that Nogo is localized on
Francesca Cialdai et al.
Cellular and molecular life sciences : CMLS, 78(23), 7795-7812 (2021-10-30)
Astronauts on board the International Space Station (ISS) are exposed to the damaging effects of microgravity and cosmic radiation. One of the most critical and sensitive districts of an organism is the eye, particularly the retina, and > 50% of astronauts develop
Monica Monici et al.
Molecular bioSystems, 9(6), 1147-1161 (2013-02-01)
Laser therapy is used in physical medicine and rehabilitation to accelerate muscle recovery and in sports medicine to prevent damages produced by metabolic disturbances and inflammatory reactions after heavy exercise. The aim of this research was to get insight into
David P J Hunt et al.
Stem cells (Dayton, Ohio), 26(1), 163-172 (2007-09-29)
Skin-derived precursor cells (SKPs) are multipotent neural crest-related stem cells that grow as self-renewing spheres and are capable of generating neurons and myelinating glial cells. SKPs are of clinical interest because they are accessible and potentially autologous. However, although spheres
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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