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Merck

MAB1987

Anti-Integrin beta 1 (CD29) Antibody

CHEMICON®, mouse monoclonal, P4C10

別名:

CD29

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この商品について

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
P4C10, monoclonal
Species reactivity:
human
Application:
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
Technique(s):
ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Citations:
74
Uniprot accession no.:
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製品名

Anti-Integrin β1 Antibody, clone P4C10, culture supernatant, clone P4C10, Chemicon®

biological source

mouse

antibody form

culture supernatant

antibody product type

primary antibodies

clone

P4C10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2a

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ITGB1(3688)

Application

Detect Integrin β1 using this Anti-Integrin β1 Antibody, clone P4C10 validated for use in ELISA, IP, WB & IC.
Inhibits attachment of UCLA-P3 cells to collagen type I (Wayner, 1991). Inhibits endodermal and keratinocytes to collagen, fibronectin and laminin. It also inhibits cell to cell adhesion. Typical dilution ranges are 1:50-1:500.

Immunoflourescence

Immunoblotting

Immunoprecipitation

ELISA

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Integrin β1 in HeLa cells.

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

Reacts with the beta-1 subunit of the integrin protein family. Appears to be human specific. Unlike many beta-1 monoclonals 4C10′s epitope is not trypsin sensitive.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Tissue Culture supernatant, containing 0.1% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

W-C Liao et al.
Placenta, 36(4), 357-364 (2015-02-11)
Glycosylation controls diverse protein functions and regulates various cellular phenotypes. Trophoblast invasion is essential for normal placental development. However, the role of glycosylation in human placenta throughout pregnancy is still unclear. The β-1,4-galactosyltransferase III (B4GALT3) has been found to regulate
M Fornaro et al.
Molecular biology of the cell, 11(7), 2235-2249 (2000-07-11)
The integrin cytoplasmic domain modulates cell proliferation, adhesion, migration, and intracellular signaling. The beta(1) integrin subunits, beta(1C) and beta(1A), that contain variant cytoplasmic domains differentially affect cell proliferation; beta(1C) inhibits proliferation, whereas beta(1A) promotes it. We investigated the ability of
Tsutomu Sato et al.
Cancer research, 65(15), 6950-6956 (2005-08-03)
CD26 is an antigen with key role in T-cell biology and is expressed on selected subsets of aggressive T-cell malignancies. To elucidate the role of CD26 in tumor behavior, we examine the effect of CD26 depletion by small interfering RNA
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site.
Trivedi, V; Boire, A; Tchernychev, B; Kaneider, NC; Leger, AJ; O'Callaghan, K; Covic et al.
Cell null
Ann-Marie Baker et al.
Journal of the National Cancer Institute, 103(5), 407-424 (2011-02-02)
Emerging evidence implicates lysyl oxidase (LOX), an extracellular matrix-modifying enzyme, in promoting metastasis of solid tumors. We investigated whether LOX plays an important role in the metastasis of colorectal cancer (CRC). We analyzed LOX expression in a patient CRC tissue

グローバルトレードアイテム番号

カタログ番号GTIN
MAB198704053252577413

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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