MAB2511
Anti-VCAM-1 Antibody, clone P8B1
clone P8B1, Chemicon®, from mouse
別名:
CD106
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
P8B1, monoclonal
Application:
—
Citations:
3
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
P8B1, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... L1CAM(3897), VCAM1(7412)
Application
Anti-VCAM-1 Antibody, clone P8B1 detects level of VCAM-1 & has been published & validated.
Function blocking
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
MAB2511 recognizes the human VCAM-1 molecule. The antibody inhibits VLA-4 (integrin alpha4beta1) binding and recognizes a different epitope than that which is recognized by MAB2144 (P3C4 clone).
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.2 M phosphate buffer to 0.25 M NaCl, pH 7.6 with 0.1% sodium azide. Caution: Sodium azide is toxic. See online MSDS.
Preparation Note
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
MAB2511:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Max L B Grönloh et al.
EMBO reports, 24(1), e55483-e55483 (2022-11-17)
Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration "hotspot" regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endothelial hotspots function to limit vascular leakage during transmigration events.
Thomas D Manes et al.
Arteriosclerosis, thrombosis, and vascular biology, 36(9), 1910-1918 (2016-07-23)
Circulating human T effector memory cell (TEM) recognition of nonself MHC (major histocompatibility complex) molecules on allograft endothelial cells can initiate graft rejection despite elimination of professional antigen-presenting cells necessary for naive T-cell activation. Our previous studies of CD4 TEM
Barbara Garmy-Susini et al.
The Journal of clinical investigation, 115(6), 1542-1551 (2005-05-20)
Neovascularization depends on vascular cell proliferation and on the stabilization of vessels by association of vascular smooth muscle-like pericytes with ECs. Here we show that integrin alpha4beta1 (VLA-4) and VCAM-1 promote close intercellular adhesion between ECs and pericytes and that
関連コンテンツ
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| MAB2511 | 04053252578380 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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