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Merck

PMB3001

L-グルタミン

99-101%, ISOM8, suitable for cell culture, from non-animal source

別名:

(S)-2,5-ジアミノ-5-オキソペンタン酸, L-グルタミン酸 5-アミド, レボグルタミド

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この商品について

化学式:
H2NCOCH2CH2CH(NH2)CO2H
CAS番号:
分子量:
146.14
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1723797
NACRES:
NA.28
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biological source

non-animal source

Quality Segment

agency

meets USP, meets requirements for USP (testing)

product line

ISOM8

assay

99-101%

form

powder

optical activity

[α]/D 31-35°, c = 2 M in HCl (10 in 2M HCl), [α]/D 6.3-7.3° in water (4 in water)

technique(s)

cell culture | mammalian: suitable

color

white

mp

185 °C (dec.) (lit.), 185 °C

solubility

water: 25 mg/mL

functional group

amide

storage temp.

room temp

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

General description

L-Glutamine is a conditionally essential amino acid. It is the most abundant free amino acid in mammalian plasma and intracellular fluids, playing a central role in nitrogen metabolism and biosynthetic pathways. Structurally, L-Glutamine is the γ-amide of glutamic acid, featuring an amide group in its side chain that enables it to function as a major nitrogen donor in a variety of metabolic reactions.

Biochem/physiol Actions

L-グルタミンは、培養細胞の主なエネルギー源となる重要な培地成分である必須アミノ酸です。L-グルタミンは、乾燥粉末および凍結溶液の状態で非常に安定です。しかし、液体培地やストック溶液において、L-グルタミンは比較的速く分解します。最適な細胞の性能には通常、使用前の培地へのL-グルタミンの添加が必要です。

Features and Benefits

Features:

1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
3. M-Clarity Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/m-clarity-program
4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
  • Site quality assessment
  • ISO 9001 certificate
  • Detailed product specifications
  • Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)


Benefits:


1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Legal Information

ISOM8 is a trademark of Sigma-Aldrich Co. LLC
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany


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保管分類

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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