504971-40
Discovery® C18 (5 µm) HPLC Columns
L × I.D. 25 cm × 4 mm, HPLC Column
別名:
C18 TM=["Discovery"] HPLC Column
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この商品について
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 4 mm
Particle size:
5 μm
Matrix active group:
C18 (RP18), C18 (octadecyl) phase
Pore size:
180 Å
Matrix:
silica gel, high purity, spherical particle platform, fully porous particle
製品名
Discovery® C18 HPLCカラム, 5 μm particle size, L × I.D. 25 cm × 4 mm
material
stainless steel column
Quality Segment
agency
suitable for USP L1
product line
Discovery®
feature
endcapped
manufacturer/tradename
Discovery®
packaging
1 ea of
extent of labeling
12% Carbon loading
parameter
≤70 °C temp. range, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
25 cm × 4 mm
surface area
300 m2/g
surface coverage
3 μmol/m2
impurities
<10 ppm metals
matrix
silica gel, high purity, spherical particle platform, fully porous particle
matrix active group
C18 (RP18), C18 (octadecyl) phase
particle size
5 μm
pore size
180 Å
operating pH range
2-8
application(s)
food and beverages
separation technique
reversed phase
General description
C18カラムを指定するあらゆる方法でDiscovery®C18カラムを使用してください。優れたピーク形状、再現性、安定性により、難しいものからルーチンまであらゆるC18カラムを用いる方法で本品を選択していただけます。
Application
- Identification, isolation and characterization of dolutegravir forced degradation products and their cytotoxicity potential.: Utilizes the Discovery® C18 HPLC Column to study the stability and degradation of the antiretroviral drug dolutegravir, crucial for ensuring drug safety and efficacy (Saida et al., 2019).
- Rapid, Refined, and Robust Method for Expression, Purification, and Characterization of Recombinant Human Amyloid beta 1-42.: This methodological study leverages the Discovery® C18 HPLC Column for the purification and analysis of amyloid beta peptides, contributing to research on Alzheimer′s disease (Prakash et al., 2019).
- Development and validation of a HPLC electrochemical detection method to measure COMT activity as a tool in drug development.: Showcases the use of the Discovery® C18 HPLC Column in developing a novel analytical method for measuring catechol-O-methyltransferase (COMT) activity, instrumental in the development of psychiatric and neurological medications (Viljoen et al., 2019).
Features and Benefits
- 優れた再現性
- 塩基性、酸性分析対象物に対する優れたピ-ク形状
- 安定で、低ブリ-ドのLC-MS分離
- ペプチドや小さなタンパク質の分離
- 多くの同等のC18カラムよりも低い疎水性で迅速な分析を提供
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable