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この商品について
実験式（ヒル表記法）:
C19H19ClN2
CAS番号:
分子量:
310.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
agency
USP
API family
desloratadine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
InChI
1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI key
JAUOIFJMECXRGI-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Desloratadine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Desloratadine Orally Disintegrating Tablets
- Desloratadine Tablets
Biochem/physiol Actions
デスロラタジンは選択的かつ非鎮静性のヒスタミンH1レセプターアンタゴニストで、ロラタジン(クラリチン)の活性型代謝産物であり、花粉症およびアレルギー症状の軽減に用いられ、他の抗ヒスタミン剤よりも眠気を催さない点が特徴です。臨床的に到達しうる血中濃度では心臓K+チャネルをほとんど阻害しません。抗ムスカリン作用/抗コリン作用を有しません。
非鎮静型のH1-受容体アンタゴニスト、抗ムスカリン／抗コリン作働性作用なし。本化合物は新たな抗アレルギー作用および抗炎症作用を有しています。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Legal Information
Clarinex is a registered trademark of Schering Corp.
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保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable