Furosemide in acute decompensated heart failure.

In a comparative clinical trial in 308 patients with acute decompensated heart failure, the relief achieved with intravenous furosemide at a dose equivalent to the daily oral dose patients were receiving prior to the acute episode was very similar to that obtained with higher doses of intravenous furosemide. Increasing the dose of intravenous furosemide did not improve the outcome.