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Merck

235474

Acridine Orange base

Dye content 75 %

동의어(들):

3,6-Bis(dimethylamino)acridine, Solvent Orange 15

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C17H19N3
CAS 번호:
Molecular Weight:
265.35
Colour Index Number:
46005
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
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form

powder

Quality Level

composition

Dye content, 75%

technique(s)

microbe id | staining: suitable

mp

165 °C (dec.) (lit.)

solubility

1 M HCl: 1 mg/mL, clear

λmax

488 nm

ε (extinction coefficient)

≥14000 at 227-233 nm, ≥20000 at 289-295 nm, ≥35000 at 486-492 nm, ≥40000 at 266-272 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C

InChI

1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3

InChI key

DPKHZNPWBDQZCN-UHFFFAOYSA-N

General description

Acridine Orange base (3,6-Bis(dimethylamino)acridine) is a cell-permeable fluorescent dye that binds to nucleic acids. It emits green fluorescence when bound to dsDNA and red fluorescence when bound to ssDNA or RNA. It is also known to be a positive solvatochromic dye.

Application

Acridine orange has also been used as a lysosomal dye. It is widely used to detect the presence of homeopathic potencies.


저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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문서 라이브러리 방문



Demethylation of Acridine Orange by Arthrobacter globiformis
Itoh K
Bulletin of Environmental Contamination and Toxicology, 60, 781-785 (1998)
Ravichandran Rekha et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 51, 191-203 (2018-11-24)
Herein, we reported a method to synthesize selenium nanowires (Cr-SeNWs) relying to purified cysteine-rich antimicrobial peptide crustin in presence of ascorbic acid. Cr-SeNWs were characterized by UV-vis, XRD, FTIR and Raman spectroscopy, as well as SEM, HR-TEM and EDAX. The
Basudev Maity et al.
European journal of medicinal chemistry, 57, 250-258 (2012-10-16)
Polypyridyl platinum(II) complexes (1-5), viz., [Pt(pyphen)Cl]Cl (1), [Pt(pyphen)(C≡CFc)]Cl (2), [Pt(pydppz)Cl]Cl (3), [Pt(pydppz)(C≡CPh)]Cl (4) and [Pt(pydppz)(C≡CFc)]Cl (5), where pyphen is 6-(2-pyridyl)-1,10-phenanthroline, pydppz is 6-(2-pyridyl)-dipyrido-[3,2-a:2',3'-c]-phenazine, FcC≡CH is ferrocenyl acetylene and PhC≡CH is phenyl acetylene, were synthesized, characterized and their DNA binding and