479675
N-(tert-Butyl)hydroxylamine acetate
97%
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(CH3)3CNHOH·CH3CO2H
CAS 번호:
Molecular Weight:
149.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C4H11NO.C2H4O2/c1-4(2,3)5-6;1-2(3)4/h5-6H,1-3H3;1H3,(H,3,4)
SMILES string
CC(O)=O.CC(C)(C)NO
InChI key
QGYZLVSWEOXOFT-UHFFFAOYSA-N
assay
97%
mp
65-69 °C (lit.)
functional group
amine, carboxylic acid
Quality Level
관련 카테고리
General description
N-(tert-Butyl)hydroxylamine acetate (NtBuHA acetate) is a derivative of hydroxylamine that shows thioesterase-mimetic and antioxidant characteristics.
Application
N-(tert-Butyl)hydroxylamine acetate has been used in a study to understand its effect on CD (cathepsin D) activity.
It may be used in the preparation of:
It may be used in the preparation of:
- (Z)-α-5-bromo-N-tert-butyl-2-methoxyphenylnitrone
- ONO-type pincer ligand
- hydroxyphenyl nitrones
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ruthenium ONO-Type Pincer Complex: Synthesis, Structural Characterization, and Catalysis.
Zhang Y, et al.
Advanced Synthesis & Catalysis, 352(10), 1779-1783 (2010)
Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.
Chavarria C, et al.
European Journal of Medicinal Chemistry, 58, 44-49 (2012)
(Z)-α-5-Bromo-N-tert-butyl-2-methoxyphenylnitrone.
Guo H, et al.
Acta Crystallographica Section E, Structure Reports Online, 63(10), 3943-3943 (2007)
Goutam Chandra et al.
Human molecular genetics, 24(19), 5416-5432 (2015-07-15)
Neurodegeneration is a devastating manifestation in the majority of >50 lysosomal storage disorders (LSDs). Neuronal ceroid lipofuscinoses (NCLs) are the most common childhood neurodegenerative LSDs. Mutations in 13 different genes (called CLNs) underlie various types of NCLs, of which the
Chinmoy Sarkar et al.
Journal of inherited metabolic disease, 43(5), 1082-1101 (2020-04-13)
Infantile neuronal ceroid lipofuscinosis (INCL) is a devastating neurodegenerative lysosomal storage disease (LSD) caused by inactivating mutations in the CLN1 gene. CLN1 encodes palmitoyl-protein thioesterase-1 (PPT1), a lysosomal enzyme that catalyzes the deacylation of S-palmitoylated proteins to facilitate their degradation
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